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From SARS to MERS: evidence and speculation
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 377-382 doi: 10.1007/s11684-016-0466-7
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths. Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.
关键词: middle east respiratory syndrome animal origin cross-species transmission monoclonal antibody
A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications
Xiaolin Fan, Yanzhen Xiong, Yuan Wang
《医学前沿(英文)》 2019年 第13卷 第5期 页码 531-539 doi: 10.1007/s11684-019-0700-1
关键词: glioblastoma cell(s) of origin neural stem cells oligodendrocyte precursor cells subventricular zone early diagnosis
In quest of the origin of ancient northern city of China: An implication from the Book of Odes
DAI Fudong
《结构与土木工程前沿(英文)》 2007年 第1卷 第4期 页码 389-392 doi: 10.1007/s11709-007-0052-9
Russian school of the theory and geometry of gearing: Its origin and golden period (1935 --1975)
Dmitry BABICHEV,Sergey LAGUTIN,Natalya BARMINA
《机械工程前沿(英文)》 2016年 第11卷 第1期 页码 44-59 doi: 10.1007/s11465-015-0360-z
During the second half of the twentieth century, Soviet scientists were among the world leaders in the theory and geometry of gearing or the theoretical fundamentals of designing gears and gear-cutting tools. The authors of the current paper review works related to the development of the theory of gearing (TG) written in Russian from the mid-1930s to the present. Overall, the review covers more than 400 publications of nearly 200 authors (among more than 1000 studied works). This review involves some works on gear strength and accuracy to attract more experts.
This paper presents a short list of works from the seventeenth century to the nineteenth century and discusses the basic concepts of the TG. This paper also includes a review of more than 160 papers in Russian for the period of 1935–1975, which is the “golden age” of the TG. The main features and achievements during this period are also considered.
The distinctive feature of this review is the use of diagrams that visually present TG experts and the dates and themes of their published works. The diagrams also show the following aspects: 1) The most popular and important themes in a specific period, 2) the most important publications on the themes of interest to readers, and 3) the direction of the works and scope of interests of every researcher.
关键词: theory of gearing (TG) gear geometry generating surface gear synthesis gear analysis
Highlights for special issue on “Large Animal Stem Cells”
Jianyong HAN
《农业科学与工程前沿(英文)》 2019年 第6卷 第1期 页码 1-2 doi: 10.15302/J-FASE-2019251
A brief review of genome editing technology for generating animal models
Haoyi WANG, Sen WU, Mario R. CAPECCHI, Rudolf JAENISCH
《农业科学与工程前沿(英文)》 2020年 第7卷 第2期 页码 123-128 doi: 10.15302/J-FASE-2019309
The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animal models. This mini-review briefly summarizes the development of major genome editing tools, focusing on the application of these tools to generate animal models in multiple species.
Cryopreservation of farm animal gametes and embryos: recent updates and progress
Zhengyuan HUANG, Lei GAO, Yunpeng HOU, Shien ZHU, Xiangwei FU
《农业科学与工程前沿(英文)》 2019年 第6卷 第1期 页码 42-53 doi: 10.15302/J-FASE-2018231
Cryopreservation has undergone tremendous advances and is widely used in animal production based on decades of study of cellular permeability, freezability and empirical generalization. Several improvement are particularly important: the cryopreservation protocol has been continuously refined over the years to achieve greater reproductive performance; cryoprotective agents are more effective and less toxic than previously; there has been significant innovation in advanced cryopreservation systems and carriers. Despite this, there are still problems that urgently require practical solutions, such as remedies for cryodamage and encouraging the use of frozen–thawed porcine sperm in pig production.
关键词: vitrification gametes embryo animal production cryoprotective agent freezability
Qi Lin, Xin Xu, Lihua, Wang, Qian Chen, Jing Fang, Xiaodong Shen, Liping Lou, Guangming Tian
《环境科学与工程前沿(英文)》 2017年 第11卷 第3期 doi: 10.1007/s11783-017-0924-8
关键词: Animal manure Biochar Metals Molecular species Pyrolysis
Highlights of special issue on Animal Science
Jun REN
《农业科学与工程前沿(英文)》 2017年 第4卷 第3期 页码 257-259 doi: 10.15302/J-FASE-2017165
Antimicrobial use in food animal production: situation analysis and contributing factors
Ziping WU
《农业科学与工程前沿(英文)》 2018年 第5卷 第3期 页码 301-311 doi: 10.15302/J-FASE-2018207
By measuring the quantity and ways in which antimicrobials are used, and reviewing different technical and socioeconomic factors influencing antimicrobial use at farm level, this study discusses the main knowledge gaps in antimicrobial use in food animal production and provides recommendations for future research and policy development. The review reveals that antimicrobial use in food animals exhibit strong regional and species differences, and there are still large information gaps concerning the current state of antimicrobial use. Factors associated with animal health (including antimicrobial resistance), animal health improvement, economic costs and benefits relevant to animal diseases, and potential technological alternatives or alternative systems all have an impact on antimicrobial use on the farm. There is a clear need to resolve the data gap by monitoring antimicrobial use and developing an analytical framework to better understand farmer behaviors under different technical, economic and environmental circumstances.
关键词: antimicrobial use drivers for antimicrobial use food animal production
Electrolyzed water and its application in animal houses
Weichao ZHENG,Li NI,Baoming LI
《农业科学与工程前沿(英文)》 2016年 第3卷 第3期 页码 195-205 doi: 10.15302/J-FASE-2016109
关键词: disinfection poultry and livestock slightly acidic electrolyzed water neutral electrolyzed water
The Origin and System Analysis of Harmonious Management for Engineering
Mao-guang Lin,Qian-kun Wang,Hua-tao Peng,Yu-dong Wang
《工程管理前沿(英文)》 2015年 第2卷 第3期 页码 241-248 doi: 10.15302/J-FEM-2015040
关键词: engineering harmony management
符友丰
《中国工程科学》 2006年 第8卷 第9期 页码 1-12
以疫病流行及其原型分析为线索,联系早期治法(如热熨、火灸、砭刺等)探讨了古代以腺鼠疫为代表的疫病流行与医学起源间的内在联系;以医源于疫的视野分析我国医史病史研究在出土文物、古文字和医学文献等方面丰富的信息资源与优势;分析解读疾病名实的古今变迁、比较中西医学及其在认识论与方法论上的差异,为审视我国传统医学在疫病防治方面的丰富经验与延至今日的独到成就与意义,疾病史研究成果与推广,实现古为今用,将为当今疫病防治的中西互补、中西医结合与比较提供宝贵的历史经验与借鉴。
Animal stem cells: the engineering development front of 2018
Wenye YUAN, Jianxiang XU, Chenying LI, Lijuan SHI, Aidong YANG, Yan WANG, Lu XING, Shaozhong KANG
《农业科学与工程前沿(英文)》 2019年 第6卷 第1期 页码 93-95 doi: 10.15302/J-FASE-2018250
陈松林,徐文腾,陈张帆
《中国工程科学》 2019年 第21卷 第6期 页码 39-47 doi: 10.15302/J-SSCAE-2019.06.007
本文主要从基因组和转录组层面分析了极地动物基因资源的研究现状,梳理了本领域研究中存在的问题,并提出了未来发展战略。极地动物基因组测序起步较晚,迄今只完成了 13种极地动物的全基因组测序。在转录组研究方面,人们对极地的 31个物种进行了转录组测序,并在以下四个方向重点开展了研究:环境适应性研究;污染物应激反应的分子机制研究;不同发育阶段或不同组织中的转录组分析;功能基因挖掘。本领域研究由于起步晚,研究广度和深度都有待加强,但极地动物的基因资源研究具有战略意义。建议国家设立“极地动物基因资源发掘与应用”重点研发计划专项,围绕极地渔业动物特殊性状遗传解析、特有基因功能分析和基因工程产品研发等开展研究。
关键词: 极地动物 基因组,转录组,基因资源
标题 作者 时间 类型 操作
A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications
Xiaolin Fan, Yanzhen Xiong, Yuan Wang
期刊论文
In quest of the origin of ancient northern city of China: An implication from the Book of Odes
DAI Fudong
期刊论文
Russian school of the theory and geometry of gearing: Its origin and golden period (1935 --1975)
Dmitry BABICHEV,Sergey LAGUTIN,Natalya BARMINA
期刊论文
A brief review of genome editing technology for generating animal models
Haoyi WANG, Sen WU, Mario R. CAPECCHI, Rudolf JAENISCH
期刊论文
Cryopreservation of farm animal gametes and embryos: recent updates and progress
Zhengyuan HUANG, Lei GAO, Yunpeng HOU, Shien ZHU, Xiangwei FU
期刊论文
The speciation, leachability and bioaccessibility of Cu and Zn in animal manure-derived biochar: effect
Qi Lin, Xin Xu, Lihua, Wang, Qian Chen, Jing Fang, Xiaodong Shen, Liping Lou, Guangming Tian
期刊论文
Antimicrobial use in food animal production: situation analysis and contributing factors
Ziping WU
期刊论文
The Origin and System Analysis of Harmonious Management for Engineering
Mao-guang Lin,Qian-kun Wang,Hua-tao Peng,Yu-dong Wang
期刊论文
Animal stem cells: the engineering development front of 2018
Wenye YUAN, Jianxiang XU, Chenying LI, Lijuan SHI, Aidong YANG, Yan WANG, Lu XING, Shaozhong KANG
期刊论文